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KMID : 0960920020010010060
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Dementia and Neurocognitive Disorders
2002 Volume.1 No. 1 p.60 ~ p.63
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A Case of Progressive Nonfluent Aphasia
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Park Kyung-Won
Kim Jae-Woo
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Abstract
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Progressive nonfluent aphasia(PA) is one of the prototypic clinical syndromes occuring in frontotemporal lobar degeneration. PA, like non-fluent type of primary progressive aphasia(PPA), is a disorder of expressive language characterized by nonfluent speech disturbance, phonologic and grammatical errors, and anomia. We report a patient who presented with progressive word-fiding difficulty, nonfluent spontaneous speech and behavioral changes. Neuropsychological and language tests demonstrated severe nonfluent aphasia with attention deficit and frontal lobe dysfunctions. Brain MRI images showed prominet altrophy in the left perisylvian area. Cerebral pefusion SPECT revealed hypoperfusion in both frontotemporal area, predominant on the left side. We suggest that PA might be differentiated from non-fluent type of PPA in that frontal lobe dysfunction develope early in the course of the illness.
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KEYWORD
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Progressive nonfluent aphasia, Frontotemporal lobar degeneration
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